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NAC is readily absorbed in the gastrointestinal tract, but there are contradictory research findings as to whether NAC can cross cell membranes and the bloodbrain barrier directly or whether it crosses as cysteine after de-acetylation

In the context of natural small-molecule compounds, their structural diversity, low toxicity, and ability to regulate multiple pathways confer unique advantages in ferroptosis intervention, particularly for the long-term treatment of chronic neurodegenerative diseases

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Toxins from environmental pollutants, processed foods, alcohol consumption, and smoking can deplete glutathione stores in the body